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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAMK2D All Species: 31.82
Human Site: S182 Identified Species: 70
UniProt: Q13557 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13557 NP_001212.2 499 56369 S182 A G T P G Y L S P E V L R K D
Chimpanzee Pan troglodytes XP_001146252 478 54096 Q168 A I E V Q G D Q Q A W F G F A
Rhesus Macaque Macaca mulatta XP_001096573 512 57729 S182 A G T P G Y L S P E V L R K D
Dog Lupus familis XP_853406 523 58964 S182 A G T P G Y L S P E V L R K D
Cat Felis silvestris
Mouse Mus musculus Q6PHZ2 499 56351 S182 A G T P G Y L S P E V L R K D
Rat Rattus norvegicus P15791 533 60062 S182 A G T P G Y L S P E V L R K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZKI0 479 54184 S182 A G T P G Y L S P E V L R K D
Frog Xenopus laevis Q9DG02 475 53914 Q167 A I E V Q G D Q Q A W F G F A
Zebra Danio Brachydanio rerio Q6DEH3 491 55810 S181 A G T P G Y L S P E V L R K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00168 530 59901 S182 A G T P G Y L S P E V L K K E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P93759 530 60036 M222 I V G S P Y Y M A P E V L R R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.5 92.9 90.8 N.A. 100 92.6 N.A. N.A. 94.5 92.1 87.3 N.A. 74.1 N.A. N.A. N.A.
Protein Similarity: 100 95.1 93.3 91.1 N.A. 100 93.2 N.A. N.A. 95.5 94.1 91.9 N.A. 82.4 N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 100 N.A. 100 100 N.A. N.A. 100 6.6 93.3 N.A. 86.6 N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. N.A. 100 6.6 100 N.A. 100 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 91 0 0 0 0 0 0 0 10 19 0 0 0 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 55 % D
% Glu: 0 0 19 0 0 0 0 0 0 73 10 0 0 0 19 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 19 0 19 0 % F
% Gly: 0 73 10 0 73 19 0 0 0 0 0 0 19 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 10 73 0 % K
% Leu: 0 0 0 0 0 0 73 0 0 0 0 73 10 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 73 10 0 0 0 73 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 19 0 0 19 19 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 64 10 10 % R
% Ser: 0 0 0 10 0 0 0 73 0 0 0 0 0 0 0 % S
% Thr: 0 0 73 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 0 19 0 0 0 0 0 0 73 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % W
% Tyr: 0 0 0 0 0 82 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _